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June 2014 Expenditures
Hey! Turns out June was a really great frugal month for us! I was a little scared to open the month’s spreadsheet because we had a few unexpected/abnormal expenditures, including the wretched dry cleaners, surprise Doctor’s appointments, and a lovely Father’s Day lunch. Plus, our darling... -
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Weekly Woot & Grumble: The Tale Of Our AC
Happy Fourth of July to our US contingent! I was trying to think of an extremely clever way to weave our nation’s independence into a post about financial independence (working title: The Fireworks of Financial Independence) but, well, that didn’t so much pan out. Although in honor of the day I... -
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Great Trash Finds: The First Edition
Mr. Frugalwoods and I are not above taking things out of the trash–in fact, quite the opposite. We fancy ourselves experts in the procurement of others’ unwanted goods, specifically those found on the side of the road. After all my frugal friends, why pay when you can find it free?!? Am I right... -
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Hiking: The Perfect Frugal Day
It’s glorious summer in New England, which lasts about 11 minutes before we return to epic winter, so we’re relishing the great outdoors. All around us, people are dropping dough on kayak rentals, croquet sets, badminton shuttlecocks, pool noodles, and sunscreen (just rub some free mud on your... -
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Weekly Woot & Grumble: 82% Savings, Anxiety & Some Rot
P.S. I’m starting off with a P.S. because this is my Woot & Grumble and we’ve already established that I don’t follow prescribed codes of conduct very well. When I sat down to pen my Weekly Woot & Grumble last night, I experienced mild anxiety. Why? Well, for the first time in our little blog’s... -
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Breakfast: The Hidden Destroyer
Of your grocery budget, that is. Reflecting on how we got ourselves to an 82% savings rate, we realized that our grocery budget played a starring role in the reductions. And one of the largest culprits on our shopping list: breakfast. We were buying three different types of breakfasts to enjoy... -
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More Than You Ever Wanted to Know About the Frugalwoods Family
Welcome! We’re ex-urban, rookie homesteaders finding contentment (and a lot of chores) on 66 acres in rural central Vermont along with our our two young daughters. I’m Liz, better known as Mrs. Frugalwoods, and I write about a wide range of topics, including my experiences as a parent, my... -
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Weekly Woot & Grumble: Liebster Award -n- Conference
Woot This week’s woot is courtesy of a very thoughtful recognition from Bee over at The Barefoot Budgeter who nominated our lil ol’ blog for a Liebster Award. Thank you Bee! I am honored! Here are the hilarious and deeply generous things Bee said about us: “This really is one of my favorite... -
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Frugal Hound Sniffs: An Interview Series
Uh, not sure how this got published, we seem to have a breach in security here at Frugalwoods. I’ll just leave this here without further comment. -Mrs. Frugalwoods Hello readers, Frugal Hound here. I know my humans think my only contribution to Frugalwoods is my photos, but I’m here to tell... -
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How Does Free Yoga Help Our Financial Goals?
Yoga is what grounds me. It keeps me from falling off the deep end of my thoughts. It curbs stress, annihilates anxiety and makes me centered, focused, and at peace. My yoga studio offers free classes in exchange for receptionist work, so I staff the check-in desk for 30 minutes once a week. I... -
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Travel Cheap By Being A Thanksgiving Weirdo
Do you want to travel internationally? Do you want to save money doing so? Would you like to see a photo of a windmill? If you answered yes to any of these questions, this post is for you! I seem to be on a “writing about our hobbies” kick, so I thought I’d continue in this vein by delving into... -
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How to Replace Exterior Window Trim
Welp, we had some rot. Specifically, the trim around one of our exterior windows was rotting away. How can you tell if window trim is rotting away? It feels like a sponge when you poke it. Wood is not supposed to resemble a sponge. Since winter is coming (don’t laugh, we have embarrassingly... -
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Preparation is the Key to Successful Scaleup
Setting the right priorities and having an overarching leadership structure was key to the successful scaleup of an advanced therapy product. That’s the message of a case study recently presented by Legend Biotech. According to Sarah Snykers, PhD, senior director of CAR-T operations at Legend...- Hoca
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New Analytics ID Metabolite Variations Tied to CHO Cell Efficiency
Chinese hamster ovary (CHO) cells were the protein production platform used in 89% of the biologics drugs approved between 2018 and 2022, and their use does not appear to be slowing. Manufacturers are turning to continuous cell culturing to meet demands, but that alone cannot create enough...- Hoca
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Life Sciences AI and Compliance: Trust But Rigorously Verify
Guest Commentary Artificial intelligence (AI) continues to upend how businesses operate, and the life sciences field is no exception. Generative AI provides life sciences companies the ability to identify and learn from patterns in large data sets. This use of AI has clear applications for the...- Hoca
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Secure AI Collaboration Will Fine-Tune OpenFold3 with Proprietary Data
“Public data is hitting its limit. The real breakthroughs can only happen through increased amounts of data and of course, tapping into industrial data,” so says Robin Roehm, CEO and co-founder of Apheris, a Berlin-based start-up focused on enabling governed, private, and secure access to data...- Hoca
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Experts Discuss Guardrails for Heritable Human Genome Editing
Around 2018–19, there was not a bigger science and ethical story than the debate over heritable human genome editing (HHGE) and the scandal over the “CRISPR babies.” The scientist, He Jiankui, who attempted to engineer the germline of human embryos, resulting in the birth of twin girls in late...- Hoca
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Danaher-IGI Beacon for CRISPR Cures Celebrates One-Year Anniversary
Berkeley—Nobel Laureate Jennifer Doudna, PhD, professor of biochemistry, biophysics, and structural biology at UC Berkeley, aspires for “CRISPR to become the standard of medical care for certain diseases” when asked for her dream for the technology in the next 5–10 years. That dream has...- Hoca
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Digital Twin Focuses on Improving Viral Vector Production
A mathematical model could help reduce the experimental effort needed to develop production processes for gene therapies. The digital twin, developed by a team at University College London (UCL) in collaboration with Volker Hass, PhD, at Furtwangen University in Germany aims to improve on...- Hoca
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Process Intensification Driving Innovation in Media Design
Culture media is fast becoming a limiting factor for intensified drug production. Overcoming this hurdle will require a combination of novel feed designs and innovative technologies. The observation comes from Dong-Yup Lee, PhD, director of the White Bioinnovation Research Center at...- Hoca
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